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Denali Therapeutics | Company Profile

11/22/2025

Contact Information

👤
Denali Therapeutics
🏢
Denali Therapeutics
📍
161 Oyster Point Blvd, South San Francisco, California 94080, US

Industry & Market

Primary Industry
research
All Industries
researchbiotechnology
Location
South San Francisco, California, United States
Public Trading
NASDAQ: DNLI

Company Metrics

👥Total Employees
215
⚙️Engineering
28
💼Sales Team
N/A
📈Marketing
3
📅Founded
2015
💰Revenue
330.5M

Funding Information

Market Cap
$2.2B
Annual Revenue
$330,531,000
Publicly traded company

Headcount Distribution

Total Employees
215
Departments
19

By Department

Department Breakdown

Education
Operations
Engineering
Information Technology
Finance
Business Development
Others

Technology Stack

Analytics & Tracking

Google AnalyticsGoogle Tag Manager

Video & Media

YouTube

Email & Communication

GmailOutlook
Total: 21 technologies

Keywords & Focus Areas

biotechnologyneurodegenerative diseaseneurodegenerationpharmaceuticalsbiotechnology: biological products (no diagnostic substances)health carebiotechnology researchregulatory compliancebrain-targeted biologicsneurodegenerative diseasespatient outcomesparkinsonsblood-brain barrier penetrationbiomarker monitoringdrug discoveryreceptor-mediated transcytosisrare diseasesmps iidrug engineeringbiomarker-driven development+10 more
30 total keywords

Denali Therapeutics

Overview

Denali Therapeutics is a clinical-stage biopharmaceutical company based in South San Francisco, California. The company is dedicated to discovering and developing therapies for neurodegenerative and lysosomal storage diseases, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). Denali leverages scientific insights into the genetic and biological mechanisms of these conditions to create effective treatments.

The company specializes in engineering therapies that can cross the blood-brain barrier, a key challenge in treating brain diseases. Its portfolio includes several drug candidates, such as DNL310 for Hunter syndrome, DNL151 for Parkinson's disease, and DNL919 for Alzheimer's disease. Denali collaborates with major pharmaceutical companies to enhance drug development efforts and is committed to improving patient outcomes through rigorous research and innovative delivery technologies.

Basic Information

Industry research
Founded 2015
Revenue 330.5M
Headquarters 161 Oyster Point Blvd, South San Francisco, California 94080, United States
Languages English

Contact Details

Key Focus Areas & Initiatives

  • Biotechnology research
  • Discovering and developing therapies for neurodegenerative diseases
  • Lysosomal storage disease therapeutics
  • Engineering therapies to cross the blood-brain barrier
  • Drug candidates: DNL310, DNL151, DNL919
  • Partnerships and collaborations with pharmaceutical companies
  • Clinical trial development
  • Biomarker-driven research
  • Patient-focused outcomes improvement
  • Innovative drug delivery platforms
  • Translational medicine and genetic validation
  • Therapeutics for rare diseases (e.g., MPS II, MPS IIIA)
  • Neuroscience research and clinical pipeline expansion

Technologies Used

  • Amazon AWS
  • Circle
  • CloudFlare Hosting
  • Drupal
  • Gmail
  • Google Analytics
  • Google Apps
  • Google Tag Manager
  • Greenhouse.io
  • MailChimp SPF
  • Microsoft Office 365
  • Mobile Friendly
  • New Relic
  • Outlook
  • React
  • Remote
  • Salesforce
  • Segment.io
  • Sigma
  • Typekit
  • YouTube

Affiliated Organizations & Regional Branches

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