March Biosciences | Company Profile
March Biosciences
Overview
March Biosciences is a clinical-stage biotechnology company based in Houston, Texas, focused on developing CAR-T cell therapies for hematological cancers, particularly T-cell lymphomas. Dedicated to transforming patient care, the organization explores innovative therapeutic targets to address conditions with limited treatment options and poor prognosis.
Their lead product, MB-105, is a first-in-class CD5-targeted CAR T-cell therapy designed for patients with relapsed or refractory CD5-positive T-cell lymphoma. MB-105 aims to selectively eliminate malignant CD5-positive cells while preserving healthy T-cell populations, minimizing on-target, off-tumor toxicity. Following the completion of a Phase 1 trial with durable responses and a favorable safety profile, March Biosciences is advancing to a multi-center Phase 2 trial in early 2025, supported by significant funding and commitments to clinical development.
Basic Information
| Industry | biotechnology |
|---|---|
| Headquarters | 2450 Holcombe Blvd, Suite X, Houston, TX 77021, United States |
Contact Details
- Phone: +1 713-898-0838
- Website: march.bio
- LinkedIn: linkedin.com/company/march-biosciences
Key Focus Areas & Initiatives
- t-cell lymphoma
- car-t cell therapy
- immunotherapy
- target-unlock technology
- pharmaceuticals
- clinical trials
- gene editing
- engineering insights
- cell quality
- medical research
- clinical development
- cd5 car t-cell
- cell therapy
- relapsed/refractory
- clinical-stage
- target validation
- clinical pipeline
- minimal cell manipulation
- hematological cancers
- cell therapy innovation
- oncology
- biotechnology
- target discovery
- high-impact targets
- streamlined manufacturing
- t-cell malignancies
- target space
- cancer treatment
- car t-cell
- biotech
- cell engineering
- target unlocking
- healthcare
- manufacturing process
- cell manufacturing
- fratricide resistance
- biological insights
- off-tumor toxicity
- b2b
- research and development in the physical, engineering, and life sciences
- patient care
- medical technology
- medical
- health care
- health, wellness & fitness
- hospital & health care
Technologies Used
- Apache
- DigitalOcean
- Gmail
- Google Apps
- Google Font API
- Google Tag Manager
- Microsoft Office 365
- Mobile Friendly
- Python
- Remote
- Shutterstock
- Ubuntu
- WordPress.org
- reCAPTCHA
Affiliated Organizations & Regional Branches
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